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MOTS-c

MOTSc · 5 mg / vial

MOTS-c

$54 AUD

Low stock

Exercise-mimetic peptide — studied for fat burning, insulin sensitivity and endurance without the workout.

Purity
≥ 99.3%
Dose
5 mg / vial
Form
Lyophilized
QC
HPLC + MS

What it does

MOTS-c is a 16-amino-acid peptide encoded by mitochondrial DNA. It is studied as a regulator of metabolic homeostasis, insulin sensitivity and exercise-like signaling. Research focuses on its role in communicating mitochondrial energy status to the nucleus and systemic metabolism.

How it works in the body

It functions like a messenger sent from mitochondria to the rest of the cell, telling the nucleus to adjust metabolism. In research it is studied for improving how cells respond to insulin, handle glucose and adapt to metabolic stress.

Researched benefits

  • Studied for improved insulin sensitivity and glucose handling
  • Investigated as an exercise mimetic for metabolic adaptation
  • Explored for mitochondrial-nuclear communication research
  • May support healthy aging and metabolic resilience studies
  • Relevant to obesity, diabetes and longevity research models

Typical research protocol

Reconstitution
Add 2 mL bacteriostatic water to the 5 mg vial → 2.5 mg/mL (1 pen unit = 0.025 mg / 25 mcg).
Dose
Typical research dose: 5–10 mg per week, split into daily doses of 0.5–1 mg (500–1,000 mcg).
Pen units (U-100)
At 2.5 mg/mL: 0.5 mg (500 mcg) = 20 units, 1 mg (1,000 mcg) = 40 units on a U-100 peptide pen.
Frequency
Daily for 5–7 days per week, often cycled 4 weeks on / 4 weeks off.

Recommended: use a single-use, sterile drawing syringe and needle for reconstitution — available in the accessories section.

For in-vitro research only — not for human or veterinary consumption.

Potential side effects

  • Flushing and mild nausea early in a cycle
  • Fatigue or a dip in output in the first days
  • Injection-site irritation
  • Appetite changes

Reported in published literature and research reports. Not exhaustive and not medical advice — this product is supplied for laboratory research only.

Deep dive · properties

The nerdy details 🔬

Half-life
~1–2 hours
Sequence / class
16-residue mitochondrial-encoded peptide (MT-RNR1)
Molecular weight
≈ 2,174 Da
Storage & stability
Store lyophilized vials at –20 °C for long-term storage (up to 24 months). Once reconstituted, refrigerate at 2–8 °C and use within 28 days. Protect from light and freeze/thaw cycles.

Published research

Where the data lives 📚

Linked purely for research context. Sold for laboratory use only.

MOTS-c

$54 AUD · 5 mg / vial

Research use only · Not for human or veterinary consumption