MOTSc · 5 mg / vial
MOTS-c
$70
Low stockMitochondrial-derived peptide studied for metabolic regulation and exercise mimetic effects.
- Purity
- ≥ 99.3%
- Dose
- 5 mg / vial
- Form
- Lyophilized
- QC
- HPLC + MS
What it does
MOTS-c is a 16-amino-acid peptide encoded by mitochondrial DNA. It is studied as a regulator of metabolic homeostasis, insulin sensitivity and exercise-like signaling. Research focuses on its role in communicating mitochondrial energy status to the nucleus and systemic metabolism.
How it works in the body
It functions like a messenger sent from mitochondria to the rest of the cell, telling the nucleus to adjust metabolism. In research it is studied for improving how cells respond to insulin, handle glucose and adapt to metabolic stress.
Researched benefits
- Studied for improved insulin sensitivity and glucose handling
- Investigated as an exercise mimetic for metabolic adaptation
- Explored for mitochondrial-nuclear communication research
- May support healthy aging and metabolic resilience studies
- Relevant to obesity, diabetes and longevity research models
Typical research protocol
- Reconstitution
- Reconstitute with 2 mL bacteriostatic water → 2.5 mg/mL (25 mcg per pen unit).
- Dose
- Typical research dose: 5–10 mg per week, split into daily doses.
- Pen units (U-100)
- 500 mcg = 20 units, 1 mg = 40 units on a U-100 peptide pen.
- Frequency
- Daily for 5–7 days per week, often cycled 4 weeks on / 4 weeks off.
Recommended: use a single-use, sterile drawing syringe and needle for reconstitution — available in the accessories section.
For in-vitro research only — not for human or veterinary consumption.
Deep dive · properties
The nerdy details 🔬
- Half-life
- ~1–2 hours
- Sequence / class
- 16-residue mitochondrial-encoded peptide (MT-RNR1)
- Molecular weight
- ≈ 2,174 Da
- Storage & stability
- Store lyophilized vials at –20 °C for long-term storage (up to 24 months). Once reconstituted, refrigerate at 2–8 °C and use within 28 days. Protect from light and freeze/thaw cycles.
Published research
Where the data lives 📚
- Lee C, et al. The mitochondrial-derived peptide MOTS-c regulates metabolism ↗
Cell Metabolism, 2015
Linked purely for research context. Sold for laboratory use only.
Often studied alongside
Pairs well with 💫
MOTS-c
$70 · 5 mg / vial