Selank vs Semax
Both are short intranasal peptides developed in Russia. Selank leans calming, Semax leans stimulating. They're often cycled together, but they solve different problems.
Selank
$100 · 10 mg / vial
- Best for
- Anxiety, mood, GABA modulation
- Mechanism
- Synthetic tuftsin analog — modulates GABA/serotonin without sedation
- Half-life
- Minutes systemic / hours central
- Dosing
- 250–500 mcg intranasal 1–3× daily
- Ideal timing
- AM and/or midday; avoid late evening
- Notes
- No dependence or rebound. 10–14 day cycles are standard.
Semax
$100 · 10 mg / vial
- Best for
- Focus, learning, neuroprotection
- Mechanism
- ACTH(4–10) analog — upregulates BDNF/NGF, dopaminergic tone
- Half-life
- Minutes systemic / hours central
- Dosing
- 250–600 mcg intranasal 1–2× daily
- Ideal timing
- AM, split doses before cognitive work
- Notes
- On Russia's essential medicines list for stroke recovery.