IPA · 5 mg / vial
Ipamorelin
$90
In stockSelective pentapeptide growth hormone secretagogue.
- Purity
- ≥ 99.3%
- Dose
- 5 mg / vial
- Form
- Lyophilized
- QC
- HPLC + MS
What it does
Ipamorelin is a selective pentapeptide growth hormone secretagogue that mimics ghrelin at the GHS-R1a receptor — but without ghrelin's appetite, cortisol or prolactin side-effects. It triggers a clean, short pulse of growth hormone from the pituitary and is the most-studied 'ghrelin mimetic' for recovery, body composition and sleep research, typically stacked with a GHRH analog like tesamorelin or CJC-1295 for synergistic GH release.
How it works in the body
It nudges your brain to release a short, clean burst of growth hormone — like the natural pulses your body used to make in your twenties. That helps you sleep deeper, recover from training faster, and repair skin and joints. Unlike older versions, it doesn't make you hungry or spike stress hormones.
Researched benefits
- Improved sleep quality, especially deep slow-wave sleep
- Faster soft-tissue and joint recovery from training
- Lean body composition support — modest fat loss with lean mass retention
- Enhanced skin, hair and connective tissue quality via IGF-1
- No hunger spikes, no cortisol or prolactin elevation
Typical research protocol
- Reconstitution
- Reconstitute with 2 mL bacteriostatic water → 2.5 mg/mL (25 mcg per pen unit).
- Dose
- Typical research dose: 200–300 mcg per administration.
- Pen units (U-100)
- 200 mcg = 8 units, 300 mcg = 12 units on a U-100 peptide pen.
- Frequency
- 1–3× per day — common pairing is morning, post-workout and pre-bed, stacked with a GHRH analog.
Recommended: use a single-use, sterile drawing syringe and needle for reconstitution — available in the accessories section.
For in-vitro research only — not for human or veterinary consumption.
Deep dive · properties
The nerdy details 🔬
- Half-life
- ~2 hours
- Sequence / class
- Aib-His-D-2-Nal-D-Phe-Lys-NH₂ (pentapeptide)
- Molecular weight
- ≈ 711.9 Da
- Origin
- Novo Nordisk (Raun K, et al., 1998)
- Storage & stability
- Store lyophilized vials at –20 °C for long-term storage (up to 24 months). Once reconstituted, refrigerate at 2–8 °C and use within 28 days. Protect from light and freeze/thaw cycles.
Common questions
Wait, quick question. 🙋
Why is ipamorelin considered 'selective'?
Unlike earlier GHRPs (GHRP-2, GHRP-6, hexarelin), ipamorelin binds GHS-R1a without meaningfully elevating cortisol, prolactin or aldosterone — so it produces a clean GH pulse without stress-hormone spillover.
Best time to dose?
Pulses are most useful when they mimic natural GH rhythm: pre-bed for the deep-sleep pulse, post-training for recovery, and fasted morning for a clean AM pulse.
Published research
Where the data lives 📚
- Raun K, et al. Ipamorelin, the first selective growth hormone secretagogue ↗
European Journal of Endocrinology, 1998
- Sinha DK, et al. Beyond the androgen receptor: ipamorelin and GH secretion ↗
Translational Andrology and Urology, 2020
Linked purely for research context. Sold for laboratory use only.
Often studied alongside
Pairs well with 💫
Ipamorelin
$90 · 5 mg / vial